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HomeAbout AboutWhy PENBRAYA?Risks of Meningococcal DiseaseGaps in Vaccination CoverageDosing & Recommendations Effectiveness & Safety Effectiveness
& Safety ImmunogenicitySafety ProfileIn Your Practice In Your PracticeSimplified CombinationHow to Transition to PENBRAYAPreparing PENBRAYAResources ResourcesRequest a RepresentativeHealth Plan CoverageMaterialsVideos
Prescribing InformationIndicationsPatient SiteRequest a RepLoading
Transitioning to PENBRAYAPfizer offers support for your practice every step of the wayOrdering PENBRAYA for your practice

Pfizer provides you a variety of ways to order, track, and pay for PENBRAYA.

Go to Pfizer Prime, the fastest, easiest way to order PENBRAYA anytime, anywhere

Order by phone
1-800-666-7248

Order with your wholesaler

PENBRAYA is supplied in cartons of 1 and 5 kits1

Each kit contains:

  • 1 single-dose vial of MenACWY lyophilized component
  • 1 prefilled syringe of MenB component
  • 1 vial adapter
Presentation Carton: 1 kit Carton: 5 kits
CVX code 316 316
CPT code 90623 90623
Carton NDC number 0069-0600-01 0069-0600-05
MenACWY lyophilized component 
(NDC 0069-0271-01)		 1 vial 5 vials
MenB component
(NDC 0069-0332-01)		 1 prefilled syringe 5 prefilled syringes
Vial adapter 1 vial adapter 5 vial adapters
Presentation Carton: 1 kit
CVX code 316
CPT code 90623
Carton NDC number 0069-0600-01
MenACWY lyophilized component 
(NDC 0069-0271-01)		 1 vial
MenB component
(NDC 0069-0332-01)		 1 prefilled syringe
Vial adapter 1 vial adapter
Presentation Carton: 5 kits
CVX code 316
CPT code 90623
Carton NDC number 0069-0600-05
MenACWY lyophilized component 
(NDC 0069-0271-01)		 5 vials
MenB component
(NDC 0069-0332-01)		 5 prefilled syringes
Vial adapter 5 vial adapters
Storing PENBRAYA1Before reconstitution
  • Store refrigerated at 2° C to 8° C (36° F to 46° F) in the original carton. During storage, a white deposit and clear supernatant may be observed in the prefilled syringe containing the MenB component. Store the carton horizontally to minimize the time necessary to resuspend the MenB component
  • Do not freeze. Discard if the carton has been frozen
After reconstitution
  • PENBRAYA should be administered immediately or stored between 2° C and 30° C (36° F and 86° F) and used within 4 hours. Do not freeze
CPT=Current Procedural Terminology; CVX=vaccine administered; NDC=National Drug Code.Quick links

Order, track, and pay for PENBRAYA with Pfizer Prime

 Order now Loading Dosing and Recommendations

Learn about ACIP-recommended dosing for PENBRAYA

 See dosing Loading Preparing PENBRAYA

See the benefits of the PENBRAYA Needle-Free* Reconstitution Kit

*Needle for administration is not included.

 Get started Loading Why PENBRAYA?

PENBRAYA offers the broadest MenABCWY protection in a single vaccine product

 Find out more LoadingCircle icon of syringe representing dosing and recommendations Dosing and Recommendations

Learn about ACIP-recommended dosing for PENBRAYA

 See dosing LoadingCircle icon of hand Preparing PENBRAYA

See the benefits of the PENBRAYA Needle-Free* Reconstitution Kit

*Needle for administration is not included.

 Get started LoadingCircle icon of hand Why PENBRAYA?

PENBRAYA offers the broadest MenABCWY protection in a single vaccine product

 Find out more Loading

Reference: 1. PENBRAYA [prescribing information]. New York, NY: Pfizer Inc.; 2023.

To report an adverse event, please call 1-800-438-1985

Pfizer for Professionals 1-800-505-4426

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Indications
  • PENBRAYA is indicated for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroups A, B, C, W, and Y. PENBRAYA is approved for use in individuals 10 through 25 years of age
  • TRUMENBA is indicated for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. TRUMENBA is approved for use in individuals 10 through 25 years of age 
Important Safety Information
  • Do not administer PENBRAYA or TRUMENBA to individuals with a history of severe allergic reaction (eg, anaphylaxis) to any component of PENBRAYA or TRUMENBA. Appropriate medical treatment used to manage allergic reactions must be available in the event an anaphylactic reaction occurs immediately following administration of PENBRAYA or TRUMENBA
  • Syncope (fainting) may occur in association with administration of injectable vaccines, including PENBRAYA or TRUMENBA. Procedures should be in place to avoid injury from fainting
  • Some individuals with altered immunocompetence may have reduced immune responses to PENBRAYA or TRUMENBA
  • Individuals with certain complement deficiencies and individuals receiving treatment that inhibits terminal complement activation are at increased risk for invasive disease caused by N. meningitidis groups A, B, C, W, and Y, even if they develop antibodies following vaccination with PENBRAYA
  • Individuals with certain complement deficiencies and individuals receiving treatment that inhibits terminal complement activation are at increased risk for invasive disease caused by N. meningitidis group B, even if they develop antibodies following vaccination with TRUMENBA
  • Vaccination with PENBRAYA or TRUMENBA may not protect all vaccine recipients
  • Vaccination with PENBRAYA does not substitute for vaccination with a tetanus toxoid–containing vaccine to prevent tetanus
  • Guillain-Barré syndrome (GBS) has been reported in temporal relationship following administration of another US-licensed meningococcal quadrivalent polysaccharide conjugate vaccine. The decision by the healthcare professional to administer PENBRAYA to individuals with a history of GBS should take into account the expected benefits and potential risks 
  • For PENBRAYA, the most commonly reported (≥15%) solicited adverse reactions after Dose 1 and Dose 2, respectively, were pain at the injection site (89% and 84%), fatigue (52% and 48%), headache (47% and 40%), muscle pain (26% and 23%), injection site redness (26% and 23%), injection site swelling (25% and 24%), joint pain (20% and 18%), and chills (20% and 16%)
  • For TRUMENBA, the most common solicited adverse reactions in adolescents and young adults were pain at injection site (≥85%), fatigue (≥60%), headache (≥55%), and muscle pain (≥35%)
  • Data are not available on the safety and effectiveness of using TRUMENBA and other meningococcal group B vaccines interchangeably to complete the vaccination series
  • The safety and effectiveness of PENBRAYA or TRUMENBA have not been established in pregnant individuals
     
Patients should always ask their healthcare providers for medical advice about adverse events. You are encouraged to report negative side effects of vaccines to the US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). Visit http://www.vaers.hhs.gov or call 1-800-822-7967.

Please see full Prescribing Information for PENBRAYA and full Prescribing Information for TRUMENBA.Indications
  • PENBRAYA is indicated for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroups A, B, C, W, and Y. PENBRAYA is approved for use in individuals 10 through 25 years of age
  • TRUMENBA is indicated for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. TRUMENBA is approved for use in individuals 10 through 25 years of age